Effective Alcoholism Treatment: the Sinclair Method

An effective alcoholism treatment is the Sinclair Method. It’s unique. It enables most alcoholics to drink in moderation. The technique uses naltrexone or a similar substance.

I. Effective Alcoholism Treatment: The Sinclair Method

Taking a pleasure blocker prevents the brain from having the pleasure of a high. Extinction then reduces craving for alcohol. Yet few people in the US have heard of the Sinclair Method.

The U.S. Food and Drug Administration (FDA) first approved naltrexone decades ago. Now other pleasure blockers are approved and can also be used.

Some Specifics

The Sinclair Method treatment lasts for three to 15 months. After that, the patient needs to continue taking naltrexone before drinking. This prevents positive conditioning from occurring. Otherwise, the extinction will die out.

Some Advantages of the Sinclair Method

    • Simple and easy.
    • No withdrawal symptoms.
    • Detox is not necessary.
    • Rehab not necessary.
    • No disruption of job or family life.
    • Can be followed with a person’s own doctor.

Avoiding a rehab is a major advantage. There is no travel, high expenses, safety concerns, or anxiety about living with strangers.

effective alcoholism treatment
Dr. John David Sinclair

Dr. John David Sinclair developed the method. It is the one used throughout Finland and widely used elsewhere. The reason it’s not widely used in the US is unclear.

It may be the very strong influence of Alcoholics Anonymous. A.A. insists that alcoholics can never learn to drink in moderation. But much scientific research for decades has proven that most alcoholics can and do learn to drink in moderation.

Most clinical trial evidence shows that the Sinclair Method may have a success rate of about 80%.1 That’s much higher than the 5% success rate of A.A. It has a self-reported success rate of about 5%. That’s only one out of 20!

Why Isn’t the Method More Widely Used?

On the Psychology Today website, addictions expert Kenneth Anderson raised an important point. “It remains difficult to understand why so few American physicians, therapists, and addiction counselors are familiar with The Sinclair Method.”

A second observer wrote it will take time for the Sinclair approach

 “to gain wider acceptance, especially in the US, where the treatment industry seems dominated by 12-step ideology. The Sinclair Method is becoming popular in other countries. It’s now available on the National Health Service in the UK. It’s also being used extensively in Scandinavian countries such as Finland, with great success. It is gaining popularity in underdeveloped countries that don’t have a pre-existing 12-step recovery treatment industry, too. It is a much cheaper solution compared to inpatient rehab and this will be attractive to countries without the infrastructure to support hospitalization for many people.”3

A third suggested that

“The medical community has been largely unconvinced of the effectiveness of this cure because of the extreme shift in mindset necessary to accept a treatment for alcoholism that involves continued consumption. To further cloud the matter, many studies have been done involving using naltrexone to help enforce abstinence – a purpose for which it is poorly suited at best. Although their ‘failure due to relapse rate’ has no bearing on the Sinclair Method, most doctors see a ‘this drug failed’ result and don’t look to see how it was used….”4

The reasons for the general lack of awareness of the Sinclair Method are unclear.

But science is the basis for the process. More important, clinical research proves its effectiveness.

II. Resources

Doctors Who Use the Sinclair Method
    • Enter “doctors who use the Sinclair method” in a search engine.
 Popular Books
    • Sinclair, J. The Sinclair Method for Treating Addiction. Shrink Rap Radio.
Journals: Effective Alcoholism Treatment
    • Heinälä, P., et al. Targeted use of naltrexone without prior detoxification in the treatment of alcohol dependence.  J Clin Pharmacol, 21(3), 287–292.
    • Sinclair, J. Evidence about the use naltrexone and for different ways of using it in the treatment of alcoholism. Alco Alco, 36(1), 2–10.
    • ________. New treatment options for substance abuse from a public health viewpoint. Ann Med, 30, 406–411.
    • ________.  Pharmacological extinction of alcohol drinking with opioid antagonists. Arqivos de Med, 12 (Suppl. 1), 95–98.
    • ________.  Development in Finland of the extinction treatment for alcoholism with naltrexone. Psychiatria Fennica, 28, 76–97.
    • ________.  Laboratory animal research in the discovery and development of the new alcoholism treatment using opioid antagonists.  Scan J Lab Animal Sci, 23 (Suppl. 1), 379–390.
    • ________. Alcoholism: Pharmacological extinction and the P-word. Työterveyslääkari, 2, 170–173.
    • ________.  From optimal complexity to the naltrexone extinction of alcoholism. In Hoffman, R., et al. (Eds.). Viewing Psychology as a Whole. Pp. 491–508.
    • Sinclair, J., et al. Long-term follow up of continued naltrexone treatment. Alco Clin Exper Res, 24 (Suppl. to No. 5), 182A.
    • ________., et al. Treatment of alcohol dependence with naltrexone utilizing an extinction protocol. Abstracts: 38th Ann Mtg, NIMH New Clin Drug Evaluation Unit (NCDEU) Program
    • ________., et al. Extinction of the association between stimuli and drinking in the clinical treatment of alcoholism with naltrexone. Alco Clin Exper Res, 22 (Suppl.), 144A.

1. Clinical Trial Evidence.

2. Anderson, K. Naltrexone and the Sinclair method of pharmacological extinction.

3. Michael D. Why Isn’t The Sinclair Method Used More Often?

4. Dombeck, M. The Sinclair Method For Treating Alcohol Dependence.

Notes: Effective Alcoholism Treatment
    • This site gives no advice about the Sinclair Method. Please see your doctor with questions.
    • Neither this site nor your host get any benefit from describing the Sinclair Method..