Alcohol’s Protective Effect on Heart: Another Possible Causal Mechanism

A review of the research literature concludes that one of the cardioprotective contributions of moderate drinking may be through a AKT/NRF2-dependent mechanism.

More specifically, consuming alcohol in moderation increases the involvement of nuclear factor (erythrioid-derived 2)-like (NFE2L2/NRF2) as well as AKT that act as regulators of oxidative balance during oxidative stress responses.

Numerous other mechanisms whereby moderate drinking contributes to improved cardiovascular health have been identified. They include the fact that:

The research evidence from around the world demonstrates that drinking alcohol in moderation causes improved health and increased longevity.

This website makes no suggestions or recommendations about any health or other matter and none should be inferred.


  • Walker, R.K., et al. The good, the bad, and the ugly with alcohol use on the heart. Alcoholism: Clinical and Experimental Research, 2013 Mar 25. doi: 10.1111/acer.12109. [Epub ahead of print]

Filed Under: Heart

This website is informational only. It makes no suggestions or recommendations about any subject.
For more fine print, read the disclaimer.